Liquid mass spectrometry (LC-MS) is also called liquid chromatography-mass spectrometry combined technology, uses liquid chromatography as the separation system and mass spectrometry as the detection system. The sample is separated from the mobile phase in the chromatographic part.After being ionized, the ion fragments are separated by mass number through analyzer of the mass spectrometer, obtained the mass spectrum by the detector. LC-MS reflects the complementarity of the advantages of chromatography and mass spectrometry, combining the high separation ability of chromatography for complex samples with the advantages of high selectivity, sensitivity and ability to provide relative molecular mass and structural information of MS. It is widely used in many fields such as medicine analysis, food analysis and environmental analysis.
High throughput; High resolution, sensitivity; Wide detection dynamic range; Simple process of sample, no derivatization required; Suitable for thermal instable less volatile, less derivatized and larger molecular substances
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