Bile Acid
Acute hepatitis, liver cirrhosis, alcoholic liver diseases, initial biliary cirrhosis, intrahepatic cholestasis of pregnancy, pediatric liver diseases and toxic liver diseases are closely related to the metabolism of bile acids. The changes of bile acids in different diseases are different. The detection of bile acid spectrum can diagnose liver and other diseases accurately. Liquid chromatography tandem mass spectrometry can effectively separate and quantitatively detect various bile acid subtypes in serum, with high detection efficiency and many detection indexes.
Detection Significance
Serum bile acid determination is a sensitive indicator for the early diagnosis of chronicity of acute hepatitis, the degree of inflammation and fibrosis of chronic hepatitis, portal hypertension of liver cirrhosis, the progression of severe hepatitis, and whether the obstruction is relieved in patients with obstructive jaundice.
Serum bile acid determination can assist in the diagnosis of inflammatory bowel disease, intrahepatic cholestasis of pregnancy, congenital biliary tract disease, liver transplantation and other diseases.
It can be used as an indicator for the monitoring of ursodeoxycholic acid and tauroursodeoxycholic acid medicine therapy.
Applicable people
- People with chronic hepatobiliary diseases, such as hepatitis C, non-alcoholic cirrhosis, gallstones or cholecystitis, non-alcoholic pancreatitis or other hepatobiliary diseases.
- Pregnant women (including maternal age > 35 years, history of oral contraceptives, history of high estrogen fertility treatment, pregnant women with twin pregnancy, pregnant women with artificial insemination).
- Digestive tract disease patients.
Detection Indicator
16 items
Cholic acid, deoxycholic acid, chenodeoxycholic acid, taurocholic acid, taurolithocholic acid, taurodeoxycholic acid, glycodeoxycholic acid, glycoursodeoxycholic acid, glycochenodeoxycholic acid, stone Cholic acid, ursodeoxycholic acid, glycocholic acid, glycolithocholic acid, tauroursodeoxycholic acid, taurochenodeoxycholic acid, total bile acids
Method Advantage
Sample Type
Serum
Blood Collection Volume
asting, whole blood 3mL
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