TDM

TDM is to determine the medicine exposure, pharmacological markers or pharmacodynamic indexes in patients, use the quantitative pharmacological model and take the medicine treatment window as the benchmark to formulate an individualized medical administration scheme suitable for patients. Its core is individualized medicine therapy. The clinical significance of TDM is to optimize the medical treatment scheme, improve the medicine efficacy, reduce toxic and side effects, and maximize the cost of medicine treatment through rational use.

Clinical Significance

Improve the effectiveness of medicine therapy

Reduce adverse medicine reactions

Assess patient compliance

Diagnosis and treatment of medicine poisoning

Reduce recurrence

Applicable People

Patients with poor clinical efficacy at recommended doses
Persons who must undergo drug concentration testing for safety reasons
Suspected patient non-adherence to medicine therapy
Concomitant medication with or suspected medicine interaction
Patients with disease recurrence when the medicine dose is sufficient

Detection Indicator

Psychotropic medicines 68 items

Lithium carbonate, clozapine, norclozapine, fluoxetine, norfluoxetine, quetiapine, trazodone, chlorpromazine, venlafaxine, desvenlafaxine, zipraside ketone, fluvoxamine, aripiprazole, dehydroaripiprazole, duloxetine, sulpiride, mirtazapine, normirtazapine, amisulpride, citalopram, desmethylcitalopram, Olanzapine, norolanzapine, escitalopram, risperidone, 9-hydroxyrisperidone, sertraline, paroxetine, haloperidol, clomipramine, norclomipramine , perphenazine, bupropion, oxybupropion, lamotrigine, fluphenazine, donepezil, levetiracetam, rivastigmine, carbamazepine, carbamazepine 10,11-ring oxide, memantine, oxcarbazepine, 10-hydroxycarbamazepine, midazolam, valproic acid, lorazepam, phenytoin, zopiclone, topiramate, clonazepam, primidone, benzene Barbital, bromoazepam, phenobarbital, nitrazepam, diazepam, nordiazepam, oxazepam, temazepam, medazepam, zolpidem, alprazolam, diamond Alkylamine, amitriptyline, nortriptyline, estazolam, doxepin, nordoxepin

19 antibiotics

Vancomycin, Voriconazole, Linezolid, Teicoplanin, Piperacillin, Fluconazole, Imipenem, Sulbactam/Cefoperazone, Meropenem, Tigecycline, Moxifloxacin, Isoniazid, entecavir, tenofovir, lamivudine, zidovudine, caspofungin, efavirenz, rifampicin

4 antitumor medicine

methotrexate, paclitaxel, docetaxel, 5-fluorouracil

5 immunosuppressive medicine

Mycophenolic Acid, Cyclosporine A, Tacrolimus, Rapamycin, Everolimus

Method Advantage

Sample Type

Serum, plasma, whole blood

Blood Collection Volume

Fasting, whole blood 3mL