PRM is an ion detection technology based on high-resolution, high-precision mass spectrometry, which can selectively detect target proteins and target peptides, so as to achieve relative or absolute quantification of target proteins or peptides.
Advantages of Technology
When the mass accuracy reaches ppm level, which can eliminate background interference and false positives better than SRM/MRM, and effectively improve the detection limit and sensitivity under complex background.
Full scan of product ions without the need for selected ion pairs and optimized fragmentation energies for easier to build methodologies
Wider linear range: increases to 5-6 orders of magnitude